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Adult stem cell-based lung organoid models emulate host immune response in fatal COVID-19 – News-Medical.Net

Recently, a team of researchers from the University of California San Diego and The Scripps Research Institute, CA, USA, showed that an integrated stem cell-bas…




Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), causes large-scale damage to the lungs triggered by a massive immune response. It causes inflammation and injury in the lungs and gives rise to diffuse alveolar damage resulting in the apoptosis of alveolar pneumocytes and pulmonary edema. The origins of this overzealous immune response are still unknown.
Although some preclinical animal models developed earlier by scientist…

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